Beyond the niacin-flush effect already covered, some people report a mild headache during the first week specifically — worth a direct, separate explanation.
Ingredients that affect blood vessel dilation can occasionally cause a mild, temporary headache as your body adjusts during the first several days, distinct from the skin-flushing reaction niacin specifically causes.
Stay well hydrated, take the capsule with food if you haven't been, and give it a few days to see if the effect settles — contact your doctor if headaches are severe, persistent, or accompanied by other symptoms.
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